Clinical Research Directory
Browse clinical research sites, groups, and studies.
Bile Acids Metabolism and Genetic Mutation Profile in the Intrahepatic Cholestasis of Pregnacy in Indian Population
Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh
Summary
Intrahepatic cholestasis of pregnancy (ICP) is a disorder characterized by itching, elevated fasting serum bile acids ≥10μmol/L (and elevated serum transaminases), with increased risks of perinatal complications, including spontaneous preterm labor, fetal distress, infant respiratory distress syndrome, meconium-stained liquor (MSL), and sudden intrauterine death (IUD). The Incidence of ICP varies from 0.1 to 15.6% of all pregnancies, with the highest cases in Chile, South Asia, America, and Scandinavia. The burden of ICP in India according to various states is as follows Punjab (3.1%), Chandigarh (4.8%), Delhi (0.79%), West Bengal (3.3%), and Lucknow (Uttar Pradesh) (2.8%).
Official title: Bile Acids Metabolism and Genetic Mutation Profile in the Etiopathogenesis of Intrahepatic Cholestasis of Pregnancy in Indian Population- A Prospective Study
Key Details
Gender
FEMALE
Age Range
21 Years - 45 Years
Study Type
OBSERVATIONAL
Enrollment
150
Start Date
2022-12-08
Completion Date
2026-07
Last Updated
2026-05-18
Healthy Volunteers
Yes
Locations (1)
Dr. Madhumita Premkumar
Chandigarh, Chandigarh, India