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SUSPENDED
NCT05695976

GRETeL: Tumor Response to Standard Radiotherapy and TMZ Patients With GBM

Sponsor: Duke University

View on ClinicalTrials.gov

Summary

The purpose of this study is to better define longitudinal genomic alterations in patients with glioblastoma (GBM), and to determine if plasma circulating tumor DNA (ctDNA) or cell free DNA (cfDNA) is associated with disease recurrence, survival, tumor characteristics, and/or peripheral immunosuppression.

Official title: A Study for Patients Newly Diagnosed With Glioblastoma Being Treated With Standard Radiotherapy and Temozolomide (TMZ) to Evaluate Tumor Response Via Liquid Biopsies (GRETeL)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

100

Start Date

2023-04-18

Completion Date

2029-01

Last Updated

2026-06-04

Healthy Volunteers

No

Locations (1)

The Preston Robert Tisch Brain Tumor Center at Duke University

Durham, North Carolina, United States