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GRETeL: Tumor Response to Standard Radiotherapy and TMZ Patients With GBM
Sponsor: Duke University
Summary
The purpose of this study is to better define longitudinal genomic alterations in patients with glioblastoma (GBM), and to determine if plasma circulating tumor DNA (ctDNA) or cell free DNA (cfDNA) is associated with disease recurrence, survival, tumor characteristics, and/or peripheral immunosuppression.
Official title: A Study for Patients Newly Diagnosed With Glioblastoma Being Treated With Standard Radiotherapy and Temozolomide (TMZ) to Evaluate Tumor Response Via Liquid Biopsies (GRETeL)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2023-04-18
Completion Date
2029-01
Last Updated
2026-06-04
Healthy Volunteers
No
Conditions
Locations (1)
The Preston Robert Tisch Brain Tumor Center at Duke University
Durham, North Carolina, United States