Clinical Research Directory

Inclusion Criteria: * The patient must be 18 years of age or older. * Patients with gastroesophageal reflux disease (GERD) who has ear, nose, and throat symptoms, chronic cough, choking, or regurgitation (food coming back up into the throat). * The patient has been diagnosed with GERD with extra-esophageal symptoms, esophagitis, hiatal hernia, achalasia, or diffuse esophageal spasm. * The patient must not be pregnant or lactating. Exclusion Criteria: * The patient cannot be younger than 18 years of age or older than 85. * The patient cannot have sleep apnea or be on CPAP * Patient cannot have previous head or neck surgery or radiation. * Patient cannot have carotid artery disease, thyroid disease or history of cerebral vascular disease. * Patients with an inability to tolerate nasal intubation. * Patients with significant bleeding disorders for whom nasal intubation has been deemed contraindicated * Patients with a known esophageal obstruction prevent passage of the manometry probe.