Clinical Research Directory

Inclusion Criteria:- - Singleton pregnancy at 34 weeks 0 days to 36 weeks 5 days of gestation at risk for / high probability of delivery in the late preterm period (34+0-36+5 weeks of gestation). Criteria for determination of late preterm delivery risk: 1. Preterm uterine contractions with intact membranes, and at least 3 cm dilation or 75% cervical effacement 2. Spontaneous rupture of the membranes 3. Expected preterm delivery for any other indication via induction or cesarean between 24 hours to 7 days after the planned randomization, as determined by the obstetric provider. \- Exclusion Criteria: They had already received a full course of betamethasone. * Expected delivery in less than 12 hours, irrespective of cause including: 1)ruptured membranes in the presence of more than 6 contractions per hour or cervical dilation of 3 centimeters or more unless oxytocin was withheld for at least 12 hours (although other induction agents were allowed), 2) chorioamnionitis, 3) cervical dilation of 8 cm or more, and 4) evidence of non-reassuring fetal status requiring immediate delivery. * Prior ACS treatment * Current known or suspected infection ( viral, bacterial or other) * Pre-gestational diabetes mellitus. * Any infection that required antibiotics or hospitalization in the month prior to study allocation - Poor understanding of the inform consent language