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ACTIVE NOT RECRUITING
NCT05699538
NA

Fatigability in Long COVID-19

Sponsor: VA Office of Research and Development

View on ClinicalTrials.gov

Summary

The overall goal of this project is to advance the understanding of underlying mechanisms impacting performance fatigability and perceived fatigability in Veterans with post-COVID-19 fatigue and explore the safety and feasibility of a home-based "minimal-dose" resistance exercise program in this population. The central hypothesis is that declines in force capacity, skeletal muscle oxygen extraction, and affective responses to physical activity offer potential mechanisms through which fatigability is increased in Veterans with post-COVID-19 fatigue. Moreover, home-based resistance exercise delivered remotely may provide a safe and feasibility treatment option for targeting neuromuscular and neurobehavioral factors influencing fatigability severity in this population.

Official title: Fatigue and Fatigability in Veterans Following SARS-CoV-2 Infection

Key Details

Gender

All

Age Range

50 Years - Any

Study Type

INTERVENTIONAL

Enrollment

21

Start Date

2023-07-31

Completion Date

2026-03-31

Last Updated

2025-09-05

Healthy Volunteers

No

Conditions

Interventions

BEHAVIORAL

Minimal-Dose Home-Based Resistance Exercise

8-week home-based resistance exercise performed one day per week.

Locations (1)

Washington DC VA Medical Center, Washington, DC

Washington D.C., District of Columbia, United States