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Motivational Behavioral and Functional MRI Impairment in Patients With Chronic Neuropathic Pain
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild
Summary
The main hypothesis of this study is that the alteration of the reward circuitry underlying the motivational deficit in chronic pain patients compared to healthy subjects results in a decrease in the capacity for reward learning. The fMRI studies have shown that this type of learning depends on the dopaminergic system innervating key regions of the reward system.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2023-12-19
Completion Date
2027-05
Last Updated
2026-01-05
Healthy Volunteers
Yes
Conditions
Interventions
reward learning task
during usual follow-up patients will complete a remard learning task questionnaire. This questionnaire cannot be assimilated to a clinical intervention.
Locations (1)
Hôpital Fondation Adolphe de Rothschild
Paris, France