Clinical Research Directory

Inclusion Criteria: * Ability to comprehend and provide a signed and dated informed consent form * Stated willingness to comply with all study procedures and attend all scheduled clinic visits, and continue participation for the duration of the study * Ability to self-administer oral medication and willingness to adhere to the medication regimen * Male or non-pregnant, non-lactating female, at least 18 years of age * Sexually active women of childbearing potential must agree to use at least one reliable method of birth control while participating in the study * Presence of fructan intolerance as determined by a positive result on a FBT within the last 6 months * Subjects who are lactose intolerant agree to eliminate all lactose from their diet during the study * Stated willingness to discontinue any medications to resolve GI symptoms (digestive enzymes, antacids, proton pump inhibitors, histamine-2 blockers, promotility agents, or anti-diarrheal agents, etc.), per the investigator's discretion. * Stated willingness to discontinue any over the counter or prescribed oral nonsteroidal anti-inflammatory drugs (NSAIDs) during the study * Per the discretion of the investigator, absence of any GI disorder other than a diagnosis of fructan intolerance Exclusion Criteria: * History of inflammatory bowel disease or active low-grade GI bacterial infection, as diagnosed by the presence of fecal calprotectin * History of celiac disease, as diagnosed by serology testing for anti-gluten protein antibodies * History of CSID, as diagnosed by the sucrose hydrogen-methane breath test, * Abnormal uncontrolled thyroid function, detected by abnormal TSH level in the blood * Per the discretion of the investigator, history of a serious physical or mental disorder * BMI greater than 30 kg/m2 * History of diabetes * History of hypersensitivity to yeast, yeast products, glycerin (glycerol), or papain