Clinical Research Directory
Browse clinical research sites, groups, and studies.
The Applanation Tonometry in GCA Pilot
Sponsor: Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Summary
The Applanation Tonometry in Giant Cell Arteritis (ATOM-GCA) study will answer the following questions: 1. How does PWV, measured by applanation tonometry of temporal arteries, differ between patients with and without a final diagnosis of GCA (based on pre-defined criteria 6 months after inclusion)? 2. What is the diagnostic accuracy and positivity cutoff of the PWV, measured by applanation tonometry, in detecting: 1. A clinical diagnosis of GCA (based on pre-defined criteria 6 months after inclusion)? 2. Inflammation of temporal arteries on high-resolution ultrasound? 3. What is the acceptability and adherence of repeat applanation tonometry during the follow-up period in patients with GCA?
Official title: The Applanation Tonometry in Giant Cell Arteritis Pilot
Key Details
Gender
All
Age Range
50 Years - 99 Years
Study Type
OBSERVATIONAL
Enrollment
146
Start Date
2025-07-30
Completion Date
2027-07
Last Updated
2025-08-07
Healthy Volunteers
No
Conditions
Interventions
Applanation tonometry
Applanation tonometry will be used to measure arterial stiffness in these segments, bilaterally: * Superficial temporal artery to frontal temporal artery * Common carotid artery to superficial temporal artery
Standardized GCA assessment
Clinical assessment, blood test review, high-resolution temporal artery ultrasound using a 24mHz probe.
Repeat applanation tonometry (optional)
Repeat index test at month 6 and at disease relapse.
Locations (1)
Vasculitis Clinic, Hopital du Sacre-Coeur de Montreal
Montreal, Quebec, Canada