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ENROLLING BY INVITATION
NCT05704309

The Diabetes Prevention Program Outcomes Study AD/ADRD Project

Sponsor: Marinella Temprosa

View on ClinicalTrials.gov

Summary

The DPPOS AD/ADRD project will address the overarching question: What are the determinants and the nature of cognitive impairment among persons with pre-diabetes (PreD) and type 2 diabetes (T2D), who are a high-risk group for cognitive impairment and represent a large fraction of the United States (US) population? This U19 proposal addresses the National Alzheimer's Project Act goal to "prevent, halt, or reverse AD" in the high-risk group of persons with pre-diabetes and type 2 diabetes, who represent over half of the population aged 60 years and older in the US.

Official title: Alzheimer's Disease and Alzheimer's Disease Related Dementias in Prediabetes and Type 2 Diabetes: The Diabetes Prevention Program Outcomes Study AD/ADRD Project

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

1976

Start Date

2022-11-07

Completion Date

2027-08-30

Last Updated

2025-08-26

Healthy Volunteers

Yes

Locations (27)

SW American Indian Center - Phoenix

Phoenix, Arizona, United States

University of California Los Angeles

Alhambra, California, United States

University of California San Diego

San Diego, California, United States

University of Colorado

Aurora, Colorado, United States

Medstar Health Research Institute

Washington D.C., District of Columbia, United States

University of Miami

Miami, Florida, United States

University of Hawaii

Honolulu, Hawaii, United States

Northwestern University

Chicago, Illinois, United States

University of Chicago

Chicago, Illinois, United States

Indiana University

Indianapolis, Indiana, United States

Pennington Biomedical Center

Baton Rouge, Louisiana, United States

Johns Hopkins University

Lutherville, Maryland, United States

Biostatistics Center, George Washington University

Rockville, Maryland, United States

Massachusetts General Hospital

Boston, Massachusetts, United States

Joslin Diabetes Center

Boston, Massachusetts, United States

Washington University

St Louis, Missouri, United States

University of New Mexico

Albuquerque, New Mexico, United States

SW American Indian Center - Shiprock

Shiprock, New Mexico, United States

SW American Indian Center - Zuni

Zuni, New Mexico, United States

Columbia University Medical Center

New York, New York, United States

Columbia University

New York, New York, United States

Albert Einstein College of Medicine

The Bronx, New York, United States

Thomas Jefferson University

Philadelphia, Pennsylvania, United States

University of Pittsburgh

Pittsburgh, Pennsylvania, United States

University of Tennessee

Memphis, Tennessee, United States

University of Texas Health Science Center San Antonio

San Antonio, Texas, United States

University of Washington, VA Puget Sound Health Care System

Seattle, Washington, United States