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Liquid Biopsies in Esophageal Cancer
Sponsor: Universitaire Ziekenhuizen KU Leuven
Summary
Purpose of this study is to determine the value of liquid biopsies, e.g. testing of minimal residual disease (MRD) by using liquid biopsies to measure circulating tumour DNA (ctDNA) at diagnosis and during the multimodal and multidisciplinary curative-intent treatment of resectable esophageal cancer.
Official title: Personalized Multimodal Treatment for Resectable Esophageal Cancer by Detecting Minimal Residual Disease Using Circulating Tumor DNA: a Multicentric Prospective Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
248
Start Date
2023-03-29
Completion Date
2026-12-31
Last Updated
2024-07-01
Healthy Volunteers
No
Conditions
Interventions
Blood sample
Retrospective collection of leftover tissue from standard of care biopsies or resection specimens and prospective collection of additional blood samples for study-specific analyses at specific timepoints, at the same time as routine labs are foreseen. No additional venipunctures are expected.
Locations (4)
UZA
Antwerp, Belgium
UZ Gent
Ghent, Belgium
UZLeuven
Leuven, Belgium
AZ Delta
Roeselare, Belgium