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Micro- and Macro-Circulation in Cardiac Surgery Patients
Sponsor: IRCCS Policlinico S. Donato
Summary
The hypothesis under the study is that there could be a link between a dysfunction in peripheral microcirculation, sublingual microcirculation or cardiovascular control and the development of post cardiac surgery major morbidities (stroke, acute kidney injury, prolonged intubation, mediastinitis, surgical reopening, death). The state of sublingual microcirculation, of peripheral microcirculation and cardiovascular control will be assessed in 100 patients undergoing cardiac surgery during general anesthesia before the intervention and at the end of the intervention at the arrival in post-surgery ICU by means of signal processing techniques. The extracted markers will be used to assess a statistical prediction model of major morbidities.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2027-01
Completion Date
2027-05
Last Updated
2026-07-07
Healthy Volunteers
No
Interventions
Acquisition of cardiovascular signals and microcirculation sidestream darkfield images
ECG, arterial pressure and peripheral flow velocity via a percutaneous laser doppler will be acquired together with images of the sublingual microcirculation detected with sidestream darkfield images microscope
Locations (1)
IRCCS Policlinico San Donato
San Donato Milanese, Milan, Italy