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Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease
Sponsor: University of Iowa
Summary
The goal of this observational study is to learn about brain development in Juvenile-onset Huntington's Disease (JoHD). The main questions it aims to answer are: * Is brain development different in JoHD than Adult-onset Huntington's Disease (AoHD)? * Can reliable biomarkers for JoHD be found in brain structure and function? Participants will be asked to complete cognitive tests, behavioral assessments, physical and neurologic evaluation, and MRI. Data collected will be compared to populations who are at-risk for HD and who have been diagnosed with HD as adults.
Official title: Longitudinal Assessment of Brain Structure and Function in Juvenile Onset Huntington's Disease (JoHD)
Key Details
Gender
All
Age Range
6 Years - 30 Years
Study Type
OBSERVATIONAL
Enrollment
40
Start Date
2020-01-01
Completion Date
2026-08-31
Last Updated
2026-03-13
Healthy Volunteers
No
Locations (6)
University of California Davis
Sacramento, California, United States
University of Iowa Hospitals and Clinics, Department of Psychiatry
Iowa City, Iowa, United States
Columbia University Medical Center
New York, New York, United States
Children's Hospital of Philadelphia with the University of Pennsylvania
Philadelphia, Pennsylvania, United States
Vanderbilt University Medical Center
Nashville, Tennessee, United States
University of Texas Health Science Center at Houston
Houston, Texas, United States