Clinical Research Directory

Inclusion Criteria: * Healthy volunteers who have given their written informed consent * Men and women from 18 to 45 years old * Normal or corrected vision * Being fluent in French or French for native language * Being affiliated with health insurance Exclusion Criteria: * Healthy volunteers who have given their written informed consent * Men and women from 18 to 45 years old * Normal or corrected vision * Being fluent in French or French for native language * Being affiliated with health insurance * Inadmissibility of the subject's consent or refusal * Working-memory deficit (as controlled with MMSE score\< 23) * Any past or current psychiatric or somatic condition(as controlled with the Mini International Neuropsychiatric Interview, MINI) * Any past or current neurological condition * History of cranio-cerebral trauma, arterial hypotension or hypertension, cardiological or serious medical condition * Abnormal potassium dosage (below 3.1 mmol/L or above 4.9 mmol/L) * Anormal ECG * History of schizophrenia or bipolar disorder in first-degree relatives * Alcohol-drinking and caffeine intake at least during 24 hours before each session * Drug therapy excepting contraceptives * Cardiologic or severe medical conditio * Pregnancy(checked with a pregnancy autotest), lactation, or insufficient contraceptive measure (precautionary measure) * Consumption of recreational drugs during the last 6 months * Known sensitivity to any of the study medication and their excipients * Lactose intolerance * Porphyria * Hepatic insufficiency