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RECRUITING
NCT05711732

Busulfan Sample Collection Study

Sponsor: Saladax Biomedical, Inc.

View on ClinicalTrials.gov

Summary

Busulfan (Busulfex®) is an alkylating drug used as a conditioning regimen prior to allogeneic hematopoietic stem cell transplantation. Busulfan has wide inter- and intra-patient pharmacokinetic variability resulting in variable exposure leading to increased risk of toxicities or sub-optimal treatment outcomes. Therapeutic drug monitoring of busulfan using patient plasma samples would benefit clinicians by providing the ability to personalize the dose to achieve a target busulfan exposure.

Official title: Collection of Plasma Samples Using Sodium Heparin From Subjects Undergoing Intravenous Busulfan Treatment

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

150

Start Date

2024-02-08

Completion Date

2026-01-31

Last Updated

2025-04-03

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

MyCare Oncology Busulfan Assay Kit

This is a sample collection study only. Patient treatment will not be determined by the outcome of the analytical test results.

Locations (2)

Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Chicago, Illinois, United States

The University of Texas MD Anderson Cancer Center

Houston, Texas, United States