CT-evaluation of Coronary Ostia Height After Surgical Aortic Valve Replacement.

ENROLLING BY INVITATION

NCT05714293

NA

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Summary

The goal of this interventional, single-center study is to demonstrate if there is a change in the coronary ostia height after surgical aortic valve replacement and if it depends on the type of prosthesis or surgical technique used. The study involves patients undergoing elective surgical aortic valve replacement with a bioprosthesis. Participants enrolled will undergo a CT scan before and after surgery (at least 90 days after surgery) to analyze coronary ostia height.

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

90

Start Date

2023-01-11

Completion Date

2026-01-10

Last Updated

2025-08-15

Healthy Volunteers

No

Conditions

Heart Valve Diseases Aortic Valve Stenosis Aortic Valve Insufficiency Regurgitation, Aortic Stenoses, Aortic Aortic Regurgitation Aortic Stenosis, Severe Coronary; Obstruction Valve Disease, Aortic

Interventions

RADIATION

CT scan with contrast medium

Multi-detector CT scan (if possible with prospective-ECG gated sequential scan) with contrast medium injection of nonionic contrast agent. All CT datasets will be analysed for the qualitative and quantitative assessment of the aortic root. The coronary height will be assessed at baseline in relation to the aortic annulus and in relation to the stent of the bioprostheses after aortic valve replacement.

Locations (1)

Policlinico Agostino Gemelli

Roma, Italy

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