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Functional Pulmonary Capillary Surface Area in BPA for CTEPH
Sponsor: Jewish General Hospital
Summary
Chronic thromboembolic pulmonary hypertension \[CTEPH\] is caused by pulmonary emboli that have enlarged in pulmonary arteries and have become organized into the vessel wall. Many patients with CTEPH are treated with balloon pulmonary angioplasty \[BPA\] which mechanically opens the narrow pulmonary arteries. It is unclear how much downstream functional pulmonary capillary surface area \[FCSA\] is recovered during BPA. The investigators plan to measure FCSAIn CTEPH patients, before and after a session of BPA.
Official title: Assessment of Recovery of Functional Capillary Surface Area in Patients Undergoing a Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2023-03-23
Completion Date
2028-01-30
Last Updated
2025-09-23
Healthy Volunteers
No
Interventions
Measurement of pulmonary functional capillary surface area
Measurement of transpulmonary metabolism of trace injected doses of benzoyl-Phe-Ala-Pro
Locations (1)
David Langleben
Montreal, Quebec, Canada