Clinical Research Directory

Inclusion Criteria: * oropharyngeal cancer diagnosis * 18 years of age and over * female or male; ratio of 1/4 toward men * had received RTH in the Department of Radiation Oncology, * reporting snoring and/or respiratory cessation complaints during sleep, Exclusion Criteria: * pregnant or breastfeeding woman; * edentation preventing retention of the oral appliance; * taking opioid or anxiolitic type medications; * history of major depression, * uncontrolled hypertension, * history of stroke; * under treatment with CPAP for sleep apnea; * regular and intense orofacial pain; * under pharmacological treatment for insomnia; * excessive alcohol or drug use (e.g., cannabis, opioid).