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E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder
Sponsor: NYU Langone Health
Summary
The purpose of this an open-label, randomized controlled trial study is to compare the effectiveness of electronic cigarettes (e-cigarettes/e-cigs) versus telehealth motivational counseling with combination nicotine replacement therapy (NRT) + telehealth counseling on combustible cigarettes smoking reduction among persons with opioid use disorder (OUD) in methadone and buprenorphine treatment programs (opioid use disorder treatment programs (OUDTP)). OUDTP patients are a population with exceptionally high combustible cigarettes smoking burden and yet limited success in achieving meaningful clinical outcomes in tobacco treatment. If effective, electronic cigarettes would provide an additional tool for tobacco harm reduction among this difficult-to-treat vulnerable population.
Official title: Effectiveness and Impact of Counseling Enhanced With Electronic Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder
Key Details
Gender
All
Age Range
21 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
302
Start Date
2024-08-08
Completion Date
2027-03-01
Last Updated
2026-03-11
Healthy Volunteers
No
Conditions
Interventions
Telehealth Motivational Counseling
At baseline, after randomization, participants will receive their first telehealth session (20\~25 minutes) from a counselor trained in motivational interviewing, harm reduction, and smoking cessation. Four additional sessions will be delivered (weeks 2, 3, 4, 6), 15\~20 minutes each.
Nicotine Replacement Product
Combination nicotine replacement therapy with lozenges and patches. Participants are recommended to use the NRT according to product directions.
National Institute on Drug Abuse (NIDA) Standardized Research Electronic Cigarette (SREC).
Participants are to use the electronic cigarette freely as replacement for smoking combustible cigarettes.
Locations (2)
NYU Langone Health
New York, New York, United States
Albert Einstein College of Medicine
The Bronx, New York, United States