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The Metabolic Effects of Intermittent Fasting
Sponsor: University of Pittsburgh
Summary
Caloric restriction has beneficial metabolic effects in humans including weight loss and improvement in blood pressure and lipid levels. Intermittent fasting has emerged as a popular alternative to caloric restriction as it does not require daily adherence to a dietary protocol, but whether the benefits of fasting protocols are dependent on weight loss is not known. In this study, the investigators will explore the metabolic effects of fasting and evaluate whether these effects, including negative effects on bone metabolism, are independent of weight loss.
Official title: The Effects of Fasting on Reprogramming of Lipid Metabolism and Bone Metabolism
Key Details
Gender
All
Age Range
21 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2023-10-25
Completion Date
2028-06-30
Last Updated
2025-08-07
Healthy Volunteers
Yes
Interventions
Fasting arm
Study participants will fast one day per week for 12 weeks
Weight maintenance
Study participants will be counseled to maintain body weight
Counseling
Study participants will be counseled on optimal diet and activity recommendations for maintaining/achieving a normal BMI
Locations (1)
University of Pittsburgh
Pittsburgh, Pennsylvania, United States