Clinical Research Directory

Inclusion Criteria: Smoker: * Participant is willing and able to give informed consent for participation in the study * Male or female, aged 50-80 years of age * No prior history of cancer, or cancer free in the last 5 years and not currently on cancer treatment * ECOG 0/1 * Current or former smokers with at least 30 pack years of smoking history * Willing to comply with study follow-up schedule and tests * Willing to cover the costs of downstream standard of care management and investigations including doctor's fee, CT scan and biopsy etc. * A Singapore citizen/Permanent Resident of Singapore Non-Smoker: * Participant is willing and able to give informed consent for participation in the study * Male, or female, aged 50-80 years of age * No prior history of cancer, or cancer free in the last 5 years and not currently on cancer treatment * ECOG 0/1 * Never smoker, or has smoked less than 10 pack-years and has quit smoking for at least 15 years * Family history of lung cancer up to 2nd degree relatives * Willing to comply with study follow-up schedule and tests * Willing to cover the costs of downstream standard of care management and investigations including doctor's fee, CT scan and biopsy etc. * A Singapore citizen/Permanent Resident of Singapore Exclusion Criteria: * Uncontrolled medical comorbidity on enrolment * Previous diagnosis of cancer * Bleeding diathesis that will preclude blood sampling * Fear of blood draw or needles * Pregnancy