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A Study of Idazoxan in Healthy Participants
Sponsor: Terran Biosciences Australia Pty Ltd
Summary
Four-part study of the safety, tolerability and pharmacokinetics of 3 forms of TR-01-XRR, 1 form of TR-01-XRS, and 1 form of TR-01-XR in healthy adults.
Official title: A Phase 1 Safety, Tolerability and Pharmacokinetic Study of R-Idazoxan HCl Extended-Release (TR-01-XRR), S-Idazoxan HCl Extended-Release (TR-01-XRS) and Racemic Idazoxan HCl Extended-Release (TR-01-XR) in Healthy Participants
Key Details
Gender
All
Age Range
18 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2023-02-14
Completion Date
2027-12
Last Updated
2026-03-18
Healthy Volunteers
Yes
Conditions
Interventions
TR-01-XRR (1)
Extended-release form
TR-01-XRR (2)
Extended-release form
TR-01-XRR (3)
Extended-release form
TR-01-XRS
Extended-release form
TR-01-XR
Extended-release form
TR-01-IR
Active comparator
Placebo
Placebo comparator
Locations (2)
Scientia Clinical Research
Randwick, New South Wales, Australia
CMAX Clinical Research
Adelaide, South Australia, Australia