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ACTIVE NOT RECRUITING
NCT05727189
PHASE1

A Study of Idazoxan in Healthy Participants

Sponsor: Terran Biosciences Australia Pty Ltd

View on ClinicalTrials.gov

Summary

Four-part study of the safety, tolerability and pharmacokinetics of 3 forms of TR-01-XRR, 1 form of TR-01-XRS, and 1 form of TR-01-XR in healthy adults.

Official title: A Phase 1 Safety, Tolerability and Pharmacokinetic Study of R-Idazoxan HCl Extended-Release (TR-01-XRR), S-Idazoxan HCl Extended-Release (TR-01-XRS) and Racemic Idazoxan HCl Extended-Release (TR-01-XR) in Healthy Participants

Key Details

Gender

All

Age Range

18 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

150

Start Date

2023-02-14

Completion Date

2027-12

Last Updated

2026-03-18

Healthy Volunteers

Yes

Conditions

Interventions

DRUG

TR-01-XRR (1)

Extended-release form

DRUG

TR-01-XRR (2)

Extended-release form

DRUG

TR-01-XRR (3)

Extended-release form

DRUG

TR-01-XRS

Extended-release form

DRUG

TR-01-XR

Extended-release form

DRUG

TR-01-IR

Active comparator

DRUG

Placebo

Placebo comparator

Locations (2)

Scientia Clinical Research

Randwick, New South Wales, Australia

CMAX Clinical Research

Adelaide, South Australia, Australia