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Intravenous Tirofiban Versus Thrombolysis Before Mechanical Thrombectomy in Stroke
Sponsor: Xinqiao Hospital of Chongqing
Summary
In patients with acute ischemic stroke secondary to large vessel occlusion, the role of intravenous adjunctive medications, such as tirofiban, or thrombolysis before endovascular thrombectomy has not been well investigated. This trial aim to evaluate the efficacy and safety of intravenous tirofiban versus thrombolysis for acute ischemic stroke patients with large vessel occlusion piror to endovascular thrombectomy.
Official title: Intravenous Adjuvant With Tirofiban Versus Thrombolysis Before Mechanical Thrombectomy in Acute Ischemic Stroke Patients With Large Vessel Occlusion: a Multicenter, Open Label, Randomized Controlled Trial.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1014
Start Date
2023-11-28
Completion Date
2026-05-25
Last Updated
2026-09-14
Healthy Volunteers
No
Conditions
Interventions
Tirofiban
Intravenous tirofiban before endovascular thrombectomy.
Thrombolysis
Intravenous thrombolysis before endovascular thrombectomy.
Locations (42)
Taihe County People's Hospital
Fuyang, Anhui, China
Yijishan Hospital of Wannan Medical University
Wuhu, Anhui, China
Longyan First Hospital of Fujian Medical University
Longyan, Fujian, China
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Guangzhou, Guangdong, China
Quanzhou County People's Hospital
Quanzhou, Guangxi, China
The First Affiliated Hospital of Hainan Medical University
Haikou, Hainan, China
Shenqiu County People's Hospital
Huaidian, Henan, China
The First Affiliated Hospital of Henan Polytechnic University (Jiaozuo Second People's Hospital)
Jiaozuo, Henan, China
Xihua People's Hospital
Wacheng Neighborhood, Henan, China
The First Affiliated Hospital, Hengyang Medical School, University of South China
Hengyang, Hunan, China
Xiangtan Central Hospital (The Affiliated Hospital of Hunan University)
Xiangtan, Hunan, China
Huai'an First People's Hospital, the Affiliated Huai'an No. 1 People's Hospital of Nanjing Medical University
Huai'an, Jiangsu, China
The 904th Hospital of The People's Liberation Army
Wuxi, Jiangsu, China
Ganzhou People's Hospital
Ganzhou, Jiangxi, China
Xingguo People's Hospital, Xinguo Hospital of Gannan Medical University
Ganzhou, Jiangxi, China
Jingdezhen First People's Hospital
Jingdezhen, Jiangxi, China
Chongzhou People's Hospital
Chongzhou, Sichuan, China
The First People's Hospital of Mianyang (Mianyang 404 Hospital)
Mianyang, Sichuan, China
Dali Bai Autonomous Prefecture People's Hospital
Dali, Yunnan, China
Changxing people's hospital
Changxing, Zhejiang, China
Haining People's Hospital
Haining, Zhejiang, China
Hangzhou First People's Hospital
Hangzhou, Zhejiang, China
Tongde Hospital of Zhejiang Province
Hangzhou, Zhejiang, China
HuZhou Central Hospital
Huzhou, Zhejiang, China
The First People's Hospital of Huzhou
Huzhou, Zhejiang, China
The First People's Hospital of Jiashan
Jiashan, Zhejiang, China
The Second Affiliated Hospital of Jiaxing
Jiaxing, Zhejiang, China
Linhai Second People's Hospital
Linhai, Zhejiang, China
Lishui People's Hospital
Lishui, Zhejiang, China
The Affiliated First Hospital of Ningbo University
Ningbo, Zhejiang, China
Ningbo Medical Center Lihuili Hospital
Ningbo, Zhejiang, China
Beilun District People's Hospital
Ningbo, Zhejiang, China
The First People's Hospital of Pinghu
Pinghu, Zhejiang, China
Affiliated Shaoxing Shangyu People's Hospital, School of Medicine, Zhejiang University
Shangyu, Zhejiang, China
Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University
Taizhou, Zhejiang, China
Taizhou Central Hospital（Taizhou University Affiliated Hospital）
Taizhou, Zhejiang, China
Taizhou municipal hospital
Taizhou, Zhejiang, China
Taizhou First People's Hospital
Taizhou, Zhejiang, China
The First People's Hospital of Tongxiang
Tongxiang, Zhejiang, China
The First People's Hospital of Wenling
Wenling, Zhejiang, China
The First Affiliated Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, China
Haiyan People's Hospital
Wuyuan, Zhejiang, China