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Trial to Compare MRI-guided Precision Prone Irradiation (PPI) Versus CT-guided Breast Irradiation
Sponsor: Weill Medical College of Cornell University
Summary
The Investigators are investigating the potential role of MRI-guided Radiation Therapy for patients receiving breast radiotherapy in the prone position with a MRI-Linac radiotherapy system, the Precision Prone Irradiation (PPI) technique. Hypothesis: The investigators would like to hypothesize that breast radiation therapy using MRI-guided system including the MRI-Linac (Arm 2) is comparable to the current standard of treatment using conventional CT-based system (Arm 1), in terms of local control of the disease at 2 year time point.
Official title: A Prospective Randomized Trial to Compare MRI-guided Precision Prone Irradiation (PPI) Versus CT-guided Breast Irradiation
Key Details
Gender
FEMALE
Age Range
50 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
17
Start Date
2023-04-03
Completion Date
2034-07-01
Last Updated
2026-01-23
Healthy Volunteers
No
Conditions
Interventions
Radiation Therapy to partial breast
Patients randomized to ARM 1 will receive 3000 cGy in 5 fractions partial breast radiotherapy with CT-based breast radiation treatment (Arm 1) and patients randomized to ARM 2 will receive 3000 cGy in 5 fractions partial breast radiotherapy with MRI-based breast radiation treatment (Arm 2).
Locations (1)
Weill Cornell Medicine
New York, New York, United States