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Steroids in Occipital Nerve Block for Treatment of Headache
Sponsor: Mayo Clinic
Summary
Currently there is limited evidence of benefit for the addition of steroids to occipital nerve blocks for treatment of headache, and not all steroids have been explored. The purpose of this research is to learn more about whether the addition of a specific kind of steroid (dexamethasone) provides any additional benefit to nerve blocks.
Official title: Treatment of Headache With Occipital Nerve Blocks: Comparison Trial of Anesthetic With or Without Dexamethasone
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2023-02-17
Completion Date
2025-06-01
Last Updated
2026-06-24
Healthy Volunteers
No
Conditions
Interventions
Bupivacaine
2 mL of bupivacaine 0.5% (5 mg/mL) injected at the origin of each bilateral greater and lesser occipital nerves
Lidocaine
0.5 mL of lidocaine 1% (10 mg/mL) injected at the origin of each bilateral greater and lesser occipital nerves
Dexamethasone
0.5 mL of dexamethasone (10 mg/mL) injected at the origin of each bilateral greater and lesser occipital nerves
Normal saline
0.5 mL of normal saline 0.9% injected at the origin of each bilateral greater and lesser occipital nerves
Greater/lesser occipital nerve blocks
Subjects will receive a total of 12 mL injectate divided equally between the 4 injection sites of the bilateral greater and lesser occipital nerves using the landmark-based technique.
Locations (1)
Mayo Clinic Minnesota
Rochester, Minnesota, United States