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Comparison of MI Paste Plus and Resin Infiltration in White Spot Lesions Following Orthodontic Treatment
Sponsor: University of Alberta
Summary
Dental cavities are among the most frequent diseases that affect teeth, particularly in patients who are treated with braces due to the difficulty in maintaining good oral hygiene in the presence of the mouth appliances. The white spot lesion (WSL) is the first clinical sign of cavities that presents itself as a milky-white opacity when located on the front face of the tooth. The aim to manage these early lesions focuses on promoting natural remineralization and preventing further demineralization. Various materials have been introduced for management of WSLs including MI paste and MI paste combined with fluoride (MI paste plus). Recently, a new material called resin infiltration has been found to treat these lesions with high esthetic results and great performance. According to the few numbers of in-vivo studies investigating the effectiveness of remineralization products, the aim of the current study is to clinically compare the outcome of the resin-infiltration and etching + MI paste plus to stop and improve the appearance of the WSL on front teeth in patients after treatment with braces.
Official title: Comparison of MI Paste Plus and Resin Infiltration in Improvement of White Spot Lesions Following Fixed Orthodontic Treatment: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
12 Years - 21 Years
Study Type
INTERVENTIONAL
Enrollment
62
Start Date
2023-05-30
Completion Date
2026-10-01
Last Updated
2025-07-04
Healthy Volunteers
Yes
Interventions
Resin infiltration
Base line treatment of white spot lesions in smooth surface with Resin infiltration -Icon + etch, DMG, Germany.
Casein Phosphopeptide (CPP) - Amorphous Calcium Phosphate (ACP) - Fluoride
Base line treatment of white spot lesions in smooth surface with MI paste plus + etch , GC corporation, Germany, Europe
Locations (1)
KAYE Edmonton Clinic
Edmonton, Alberta, Canada