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Effect of Magnesium Sulphate Pretreatment in Pediatric Abdominal Surgery
Sponsor: Assiut University
Summary
In this study, the investigators will compare the effect of magnesium sulphate pretreatment on the onset and duration of intense and deep neuromuscular Block of rocuronium versus Cis-Atracurium and on the period of no response to nerve stimulation in children undergoing elective open abdominal surgeries.
Official title: Effect of Magnesium Sulphate Pretreatment on the Onset and Duration of Intense and Deep Neuromuscular Block of Rocuronium Versus Cis-Atracurium in Pediatric Abdominal Surgery
Key Details
Gender
All
Age Range
2 Years - 12 Years
Study Type
INTERVENTIONAL
Enrollment
58
Start Date
2023-06-20
Completion Date
2025-12-01
Last Updated
2025-01-20
Healthy Volunteers
No
Conditions
Interventions
MgSO4
The patients will be pretreated with magnesium sulphate infusion (30 mg kg-1, total volume 100 ml, infusion rate 5 ml min-1) 20 min. before induction of anesthesia.
Cis-Atracurium
Cis-Atracurium will be administered at 0.1-0.15 mg/kg IV bolus for intubation and maintenance at a dose of 0.03 mg/kg iv on fixed intervals.
Locations (2)
Pediatric hospital, faculty of medicine, Assiut university
Asyut, Assiut Governorate, Egypt
Pediatric hospital
Asyut, Assiut Governorate, Egypt