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Oral Immunotherapy in Young Children With Food Allergy
Sponsor: Deventer Ziekenhuis
Summary
The goal of this clinical trial is to learn about oral immunotherapy in food allergic children \< 30 months of age. The main question it aims to answer is: What is the clinical- and cost-effectiveness of early low-dose oral immunotherapy aimed at long-term tolerance induction. Participants will receive oral immunotherapy for 1 year with a maintenance dose of 300 mg allergenic protein and are compared with food allergic infants not receiving oral immunotherapy to compare with natural tolerance development.
Official title: A Randomized Controlled Trial to Investigate the (Cost)Effectiveness of Oral Immunotherapy With Different Allergens in Young Children With an Established Food Allergy
Key Details
Gender
All
Age Range
9 Months - 30 Months
Study Type
INTERVENTIONAL
Enrollment
500
Start Date
2023-02-01
Completion Date
2027-05-01
Last Updated
2025-09-16
Healthy Volunteers
No
Conditions
Interventions
oral immunotherapy
oral immunotherapy is performed by freely available, widely used food products, regularly part of a normal infant's diet such as peanut butter or boiled egg.
Locations (4)
Deventer hospital
Deventer, Overijssel, Netherlands
Amsterdam UMC, location AMC
Amsterdam, Netherlands
Reinier de Graaf Gasthuis
Delft, Netherlands
Martini hospital
Groningen, Netherlands