Clinical Research Directory

Inclusion Criteria: 1. Ability to understand and voluntarily agrees to participate by giving written informed consent for the study; 2. Male or female aged ≥18 years and ≤75 years at the time of signing the ICF; 3. Histopathologically or cytologically documented advanced or metastatic malignancies; 4. At least 1 measurable lesion conforming to RECIST 1.1 criteria; 5. An Eastern Cooperative Oncology Group (ECOG) performance status (PS) score of 0 or 1; 6. Female and male patients of reproductive potential must agree to use highly effective contraception. Exclusion Criteria: 1. Any immunostimulants administered within 4 weeks; 2. Systemic anti-tumor therapy within 4 weeks; 3. Any investigational cancer therapy administered within 4 weeks; 4. Surgical procedures requiring general anesthesia within 4 weeks; 5. History of autoimmune diseases; 6. History of immunodeficiency; 7. Severe infections within 2 weeks prior to the first study treatment; 8. Clinically significant cardiovascular condition; 9. Prior malignancy (other than current malignant tumor) within 5 ears before the first dose of study treatment; 10. Known history of serious allergic reactions to the investigational product or its main ingredients.