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Emotional and Neutral Sounds for Neurophysiological Prognostic Assessment of Critically Ill Patients With a Disorder of Consciousness
Sponsor: Assistance Publique - Hôpitaux de Paris
Summary
The purpose of this study is to determine if the use of emotional sound as subject own name (SON) pronounced by a familiar voice (FV) compared to SON pronounced by a non-familiar voice (NFV) during event related potential (ERP) produced a more reliable neurophysiological P300 responses, and to assess the prognostic value of this P300 responses induced by the SON with a FV.
Official title: Emotional and Neutral Sounds for Neurophysiological Prognostic Assessment of Critically Ill Patients With a Disorder of Consciousness (DOC)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
114
Start Date
2024-03-25
Completion Date
2026-09
Last Updated
2025-09-12
Healthy Volunteers
No
Conditions
Interventions
Use of "expressive" sounds
Use of "expressive" sounds, that is to say the own first name pronounced by the voice of the relative to generate the P300 and a sound with an "approaching" character of the subject to generate the MMN. The investigators will thus be able to compare: * MMN: present/absent for each modality (neutral vs approaching sounds) * Wave P3a: latencies and amplitudes for each modality (own first name voice of the near vs unfamiliar).
Having benefited from a prognostic evaluation by event related potentials (without sound research methods, only neutral sounds)
Retrospective inclusion Have already had an assessment with event related potentials without "emotional" modalities (VF and similar sounds) as part of their care between April 2022 and December 2022 in intensive care at Cochin hospital.
Locations (2)
Medical ICU, HEGP Hospital, APHP.Centre
Paris, IDF, France
Medical ICU, Cochin Hospital, APHP.Centre
Paris, Île-de-France Region, France