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The Value of a Risk Prediction Tool (PERSARC) for Effective Treatment Decisions of Soft-tissue Sarcomas Patients
Sponsor: Leiden University Medical Center
Summary
The goal of this clinical trial is to assess the (cost-)effectiveness of a personalised risk assessment tool (PERSARC) to increase patients' knowledge about risks and benefits of treatment options and to reduce decisional conflict in comparison with usual care in high-grade extremity Soft-Tissue Sarcoma-patients. High-grade (2-3) extremity Soft-Tissue Sarcoma patients (\>= 18 years) will either receive standard care (control group) or care with the use of PERSARC; i.e. PERSARC will be used in multidisciplinary tumour boards to guide treatment advice and in consultation in which the oncological/orthopaedic surgeon informs the patient about his/her diagnoses and discusses the benefits and harms of all relevant treatment options (intervention group)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2021-08-24
Completion Date
2025-08-29
Last Updated
2025-09-09
Healthy Volunteers
No
Interventions
Care with the use of PERSARC
PERSARC is a personalized risk assessment tool which provides patients and STS professionals insight into the personalized risks and benefits of each treatment option based on patient's age, tumor size, tumor depth and histology. PERSARC will be used in multidisciplinary tumour boards to guide treatment advice and in consultation in which the oncological/orthopaedic surgeon informs the patient about his/her diagnoses and discusses the benefits and harms of all relevant treatment options
standard care
All patients in control condition receive usual care.
Locations (7)
Radboud UMC
Nijmegen, Gelderland, Netherlands
Maastricht UMC
Maastricht, Limburg, Netherlands
Netherlands Cancer Institue
Amsterdam, North Holland, Netherlands
UMC Groningen
Groningen, Provincie Groningen, Netherlands
Leiden University Medical Center
Leiden, South Holland, Netherlands
Erasmus MC
Rotterdam, South Holland, Netherlands
UMC Utrecht
Utrecht, Utrecht, Netherlands