Clinical Research Directory

Inclusion Criteria: * Age ≥ 18 years old; * Diagnosis of UC confirmed by clinical, endoscopic, and/or histological evidence prior to screening as per standard criteria; * Ability of subject to participate fully in all aspects of this project; * Written informed consent must be obtained and documented. Exclusion Criteria: * Suspicion of differential diagnosis of CD, indeterminate colitis, ischemic colitis, radiation colitis, diverticular disease associated with colitis, or microscopic colitis; * Serious underlying disease other than UC that in the opinion of the investigator may interfere with the subject's ability to participate fully in the study or would compromise subject safety (such as history of malignancies, major neurological disorders, certain orthopedic impairments or any unstable, uncontrolled or severe systemic medical disorder); * History of alcohol or drug abuse that in the opinion of the investigator may interfere with the subject's ability to comply with the study procedures; * History of psychiatric disorders that in the opinion of the investigator may interfere with the subject's ability to comply with the study procedures; * If female, the subject is pregnant or lactating (\< 1 year) or intending to become pregnant; * Immobilized patients who are not able to complete exercise intervention; * Illiteracy (disability to read and understand Dutch).