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RECRUITING
NCT05746039
PHASE1/PHASE2

Feasibility of Semaglutide in Advanced Lung Disease

Sponsor: University of Pennsylvania

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn whether semaglutide, an FDA-approved treatment for diabetes and obesity, is feasible and tolerable in patients with advanced lung disease. The main question\[s\] it aims to answer are: 1. Are patients with advanced lung disease able to tolerate semaglutide therapy? 2. Are we able to titrate semaglutide therapy to a target weight? Participants will be asked to perform pulmonary function, physical function and body composition testing, as well as a blood draw before and after 12-weeks of semaglutide therapy. While on therapy, subjects will be surveyed regarding any adverse events or side effects.

Official title: Feasibility of Semaglutide Therapy for Weight Loss in Advanced Lung Disease: A Pilot Study

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

8

Start Date

2024-01-29

Completion Date

2025-12-28

Last Updated

2025-03-17

Healthy Volunteers

No

Interventions

DRUG

Semaglutide Pen Injector

Once weekly subcutaneous injection

Locations (1)

University of Pennsylvania Perelman School of Medicine

Philadelphia, Pennsylvania, United States