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Feasibility of Semaglutide in Advanced Lung Disease
Sponsor: University of Pennsylvania
Summary
The goal of this clinical trial is to learn whether semaglutide, an FDA-approved treatment for diabetes and obesity, is feasible and tolerable in patients with advanced lung disease. The main question\[s\] it aims to answer are: 1. Are patients with advanced lung disease able to tolerate semaglutide therapy? 2. Are we able to titrate semaglutide therapy to a target weight? Participants will be asked to perform pulmonary function, physical function and body composition testing, as well as a blood draw before and after 12-weeks of semaglutide therapy. While on therapy, subjects will be surveyed regarding any adverse events or side effects.
Official title: Feasibility of Semaglutide Therapy for Weight Loss in Advanced Lung Disease: A Pilot Study
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
8
Start Date
2024-01-29
Completion Date
2025-12-28
Last Updated
2025-03-17
Healthy Volunteers
No
Conditions
Interventions
Semaglutide Pen Injector
Once weekly subcutaneous injection
Locations (1)
University of Pennsylvania Perelman School of Medicine
Philadelphia, Pennsylvania, United States