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Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms
Sponsor: Istituti Clinici Scientifici Maugeri SpA
Summary
The goal of this observational study is to learn about the impact of the different types of pain and of the domains involved in the autonomic disorders of inpatients and outpatients diagnosed with Parkinson disease (PD) and multiple system atrophy (MSA) admitted to Istituti Clinici Scientifici Maugeri Centers. The main aims are: Evaluate the prevalence of pain and characterize it in Parkinson's disease and atypical parkinsonisms (MSA) Evaluate the effect of rehabilitation on pain and autonomic symptoms Evaluate the prevalence of autonomic symptoms in Parkinson's disease and atypical parkinsonisms (MSA) Assess the impact of pain and autonomic symptoms on quality of life. Participants will perform neurological examination, rehabilitation program and clinical scales. Researchers will compare the two groups of patients (PD and MSA) and the effect of the rehabilitation on pain, autonomic symptoms and quality of life.
Official title: Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms: Identification of Predictive Patterns of Rehabilitation Outcome and Evaluation of the Impact on Quality of Life
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
280
Start Date
2019-06-15
Completion Date
2025-12-30
Last Updated
2025-01-30
Healthy Volunteers
No
Conditions
Interventions
Rehabilitation
All patients included in the study will undergo a basic evaluation with a neurological examination, a rehabilitation program to improve strength, coordination, balance, endurance, and the ability to perform activities of daily life.
Administration of Clinical scales
All patients included in the study will be evaluated by clinical scales assessing the disease stage, clinical severity, freezing, motor and non-motor impairment, cognitive impairment, depression, quality of life, autonomic dysfunction, pain.
Locations (9)
ICS Maugeri - IRCCS of Telese Terme
Telese Terme, Benevento, Italy
ICS Maugeri - Lumezzane
Lumezzane, Brescia, Italy
ICS Maugeri - Castelgoffredo
Castel Goffredo, Mantova, Italy
ICS Maugeri - Mistretta
Mistretta, Messina, Italy
ICS Maugeri - Veruno
Veruno, Novara, Italy
ICS Maugeri - Montescano
Montescano, Pavia, Italy
ICS Maugeri - Milano
Milan, Italy
ICS Maugeri - Pavia Boezio
Pavia, Italy
ICS Maugeri - Pavia
Pavia, Italy