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ENCALM: A Study of ENX-102 as a Monotherapy Treatment in Patients With Generalized Anxiety Disorder
Sponsor: Engrail Therapeutics INC
Summary
The ENCALM trial is designed to evaluate the efficacy and safety of ENX-102 in patients diagnosed with generalized anxiety disorder (GAD)
Official title: The ENCALM Trial: A Randomized, Double-blind, Placebo-controlled Monotherapy Trial to Evaluate the Efficacy and Safety of ENX-102 in Patients With Generalized Anxiety Disorder
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
252
Start Date
2023-07-03
Completion Date
2025-09-18
Last Updated
2026-09-21
Healthy Volunteers
No
Conditions
Interventions
ENX-102
Selective GABA-A alpha2,3,5 positive allosteric modulator
Placebo
Placebo
Locations (32)
IMA Clinical Research Phoenix
Phoenix, Arizona, United States
Collaborative Neuroscience Research, LLC (CNS)
Garden Grove, California, United States
Sun Valley Research Center
Imperial, California, United States
Alliance Research
Long Beach, California, United States
NRC Research Institute
Los Angeles, California, United States
Excell Research, Inc.
Oceanside, California, United States
Anderson Clinical Research
Redlands, California, United States
California Neuroscience Research, LLC
Sherman Oaks, California, United States
Pacific Clinical Research Management Group
Upland, California, United States
Sunwise Clinical Research
Walnut Creek, California, United States
Mountain View Clinical Research
Denver, Colorado, United States
Vertex Clinical Research
Clermont, Florida, United States
Clinical Neuroscience Solutions, Inc.
Jacksonville, Florida, United States
Accel Research Sites Network - Lakeland CRU
Lakeland, Florida, United States
Accel Research Sites Network - Maitland CRU
Maitland, Florida, United States
Clinical Neuroscience Solutions, Inc.
Orlando, Florida, United States
CenExel iResearch, LLC
Savannah, Georgia, United States
Collective Medical Research
Overland Park, Kansas, United States
Boston Clinical Trials
Boston, Massachusetts, United States
Precise Research Centres
Flowood, Mississippi, United States
IMA Clinical Research
Las Vegas, Nevada, United States
SPRI Clinical Trials, LLC
Brooklyn, New York, United States
Neurobehavioral Research
Cedarhurst, New York, United States
Richmond Behavioral Associates
Staten Island, New York, United States
Clinical Neuroscience Solutions, Inc.
Memphis, Tennessee, United States
Austin Clinical Trials Partners
Austin, Texas, United States
FutureSearch Trials of Dallas
Dallas, Texas, United States
Baylor College of Medicine
Houston, Texas, United States
Aim Trials
Plano, Texas, United States
Grayline Research Center
Wichita Falls, Texas, United States
Alpine Research Organization
Clinton, Utah, United States
Core Clinical Research
Everett, Washington, United States