Clinical Research Directory

Inclusion Criteria: * Adults aged 18-75 years. * Willing and able to sign and date the informed consent form and HIPAA form. * Have a single implant that has been successfully osseointegrated and deemed ready for restoration by the surgeon placing the implant. (A maximum of two single dental implant restorations per subject will be restored.) * Have a single implant that is acceptable to be restored with a digital workflow using the CEREC system. * Have a single implant to be restored with a screw retained advanced lithium disilicate crown. * Have a single implant with at least one adjacent tooth contact and with an occlusal contact. Exclusion Criteria: * Not willing to participate in the clinical investigation or not able to understand the content of the clinical investigation. * Unlikely to be able to comply with clinical investigation procedures according to the Principle Investigator's/Co-investigator's judgement. * Unable or unwilling to return for recall appointments for a period of 5 years. * Severe non-compliance to Clinical Investigation Protocol as judged by the PI or Co-investigators. * Women who self-report that they are possibly pregnant, pregnant, or lactating, as elective dental treatment is not indicated at these times. * Previous enrollment in the present clinical investigation. * Involvement in the planning and conduct of the clinical investigation (applies to both Dentsply Sirona personnel and from the clinical investigation site).