Clinical Research Directory
Browse clinical research sites, groups, and studies.
Comparison of CE-DBT and MRI in Patients With Known Breast Lesions
Sponsor: UNC Lineberger Comprehensive Cancer Center
Summary
The purpose of this pilot study is to compare radiologist confidence level in evaluating patients with known breast lesions between contrast enhanced digital breast tomosynthesis (CE- DBT) and contrast enhanced dynamic magnetic resonance imaging (CE-MRI) acquired as a part of a standard clinical workup.
Official title: Comparison of Contrast Enhanced Digital Breast Tomosynthesis and Magnetic Resonance Imaging in Patients With Known Breast Lesions
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2023-03-13
Completion Date
2026-08-22
Last Updated
2025-09-25
Healthy Volunteers
No
Conditions
Interventions
Iohexol 350 Mg/mL Injectable Solution
Participants will be scanned with the digital breast tomosynthesis (DBT) system before and after the intravenous administration of iodinated contrast agent, iohexol 350mg I/mL at a dose of 1.5 mL/kg body weight. Images will be acquired of the breast of interest prior to the administration of contrast, followed by at approximately 2 minutes and 5 minutes after administration. For the purposes of this study, imaging will focus on a single breast to simplify data acquisition.
Locations (1)
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States