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Effect of MgSO4 Pretreatment on Muscle Relaxation
Sponsor: Assiut University
Summary
In this study, the effect of magnesium sulphate on the onset and duration of intense and moderate cis-atracurium induced neuromuscular blocking and on the period of no response to nerve stimulation will be evaluated in patients who will recieve magnesium sulphate (intervention group) and patients who will not recieve magnesium sulphate (comparator group).
Official title: Effect of Magnesium Sulphate Pretreatment on Cis-Atracurium Induced Neuromuscular Block and Recovery Characteristics: A Randomized Controlled Trial.
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2023-07-23
Completion Date
2025-05
Last Updated
2024-07-01
Healthy Volunteers
No
Conditions
Interventions
Magnesium Sulphate
A magnesium sulphate infusion (60 mg kg-1, total volume 100 ml, infusion rate 10 ml min-1) will be administered to patients 10 min. before induction of anesthesia.
Saline
The patients will be pretreated with an intravenous 0.9% saline infusion (total volume 100 ml, infusion rate 10 ml min-1) 10 min before induction of anesthesia.
Locations (1)
Assiut university main hospital, ENT operative theatre
Asyut, Asyut Governorate, Egypt