Clinical Research Directory

Inclusion Criteria: * Men or women aged \>18 years of any race/ethnicity * Elevated BP or hypertension at screening (untreated office systolic BP 120-159 and diastolic BP \<100 mm Hg) * Willing and able to provide informed consent Exclusion Criteria: * Medical condition in which potassium supplementation is contraindicated: history of heart failure, myocardial infarction, stroke, cardiac arrythmia, chronic kidney disease or estimated glomerular filtration rate \<60 ml/min/1.73 m\^2, diabetes or non-fasting glucose \>200 mg/dL, major depressive disorder (PHQ-9 score ≥15), psychosis, ulcer diseases including esophageal-gastric ulcer, malignancy in the past 5 years, liver disease, organ transplant, Addison's disease (adrenal insufficiency) * Use of medications which may alter serum potassium levels or in which potassium supplementation is contraindicated: antihypertensive agents, antihistamines, antiparkinson agents, antimuscarinic agents, antipsychotics, muscle relaxants, systemic corticosteroids, or chronic use of non-steroidal anti-inflammatory drugs * Serum potassium ≥5.0 mEq/L * Metabolic acidosis * Consumption of \>85th percentile of usual potassium intake among US adults (\>3,750 mg/day) * For women, current pregnancy, breastfeeding, or plans to become pregnant during the study * Consumption of ≥21 alcoholic beverages per week or consumption of ≥6 beverages per occasion * Current or planned residence making it difficult to meet trial requirements or travel to the study site * Current participation in another intervention or pharmaceutical trial * Unable or unwilling to complete 24-hour BP or urinary sample collection * Other concerns regarding ability to meet trial requirements, at the discretion of the investigators or staff