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CT TAVR Abdomen Study
Sponsor: University of Maryland, Baltimore
Summary
A standard polyenergetic CT (computed tomography) procedure utilizes 100 ml of iodinated contrast. A recent world-wide shortage of iodine based intravenous contrast has highlighted the need to search for alternative methods or doses. Reducing iodinated IV contrast dose can mitigate IV contrast supply shortages and enable significant cost savings for the radiology practice and hospital system. In addition, decreased IV contrast dose can potentially reduce the rate of acute kidney injury, specifically in patients with decreased renal function. The purpose of the study is to determine whether low IV contrast dose CT with monoenergetic reconstruction can be use for presurgical planning of transcatheter valve replacement (TAVR) procedure.
Official title: Dual Energy CT Decreased IV Contrast Dose Imaging for TAVR
Key Details
Gender
All
Age Range
18 Years - 88 Years
Study Type
INTERVENTIONAL
Enrollment
164
Start Date
2023-09-19
Completion Date
2027-03-01
Last Updated
2025-04-24
Healthy Volunteers
Yes
Conditions
Interventions
Iodinated Contrast Agent (Omnipaque)
Standard dosage of Omnipaque for CT imaging is 100 ml. Cohort will be given a reduced dosage.
Dual Energy CT
Dual energy CT scanners enable monoenergetic CT image reconstruction which allows for improved iodine image contrast.
Locations (1)
University of Maryland Medical Center
Baltimore, Maryland, United States