Clinical Research Directory

Inclusion Criteria: * Age ≥21 * Subject must have apical with anterior or posterior vaginal prolapse with leading edge of prolapse to or beyond the hymen * Subject reports a bothersome bulge they can see or feel per Pelvic Floor Disability Index (PFDI-20), question 3, response of 2 or higher * Eligible for laparoscopic or robotic sacrocolpopexy * Desires surgical treatment for symptomatic uterovaginal or vaginal vault prolapse * English speaking Exclusion Criteria: * Patients who are not surgical candidates due to medical comorbidities * Current foreign body complications (including but not limited to erosion, fistula, abscess). This covers foreign bodies of any type (e.g. synthetic and biologic including allograft, xenograft). * Inability to give informed consent or to complete the testing or data collection. * Anticipated circumstances resulting in an inability to follow up (geographic relocation, etc.). * Active systemic infection including any gynecologic infection, untreated Urinary Tract Infection (UTI) or tissue necrosis. * History of pelvic organ cancer (e.g. uterine, ovarian, bladder, or cervical). * Prior or currently undergoing radiation, laser therapy, or chemotherapy in the pelvic area. * Subject has taken systemic steroids (within the last month, steroid inhalers OK), or immunosuppressive or immunomodulatory treatment (within the last 3 months) * Systemic connective tissue disease (e.g. scleroderma, Marfan's syndrome, Ehlers Danhlos, collagenosis, polymyositis or polymyalgia rheumatic, lupus) * Chronic systemic pain that includes the pelvic area or chronic focal pain that involves the pelvis * Poorly controlled diabetes mellitus (DM), as indicated by Hemoglobin A1c \> 9 * Those requiring concomitant rectopexy * Subject is not able to conform to steep Trendelenburg position * Known sensitivity to polypropylene * History of prior prolapse repair utilizing vaginal or abdominal mesh * Planned vaginal mesh attachment placed transvaginally * History of diverticulitis