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Bimanual Motor Skill Learning in Acute Stroke
Sponsor: University Hospital of Mont-Godinne
Summary
The subacute phase of stroke provides a window into how a lesion perturbs sensorimotor functions prior to reorganisation driven by plasticity and neurorehabilitation. The recovery from motor impairment has been extensively studied, but it is currently unknown whether motor skill learning (MSkL) is enhanced or impaired during acute stroke, especially bimanual motor skill learning (bim-MSkL), which likely requires more motor-attentional-cognitive resources than unimanual MSkL. The goals of this project are: to determine the neural substrates critical to achieve proximal and distal bimanual motor skill learning (bim-MSkL) by specifying whether (sub)acute stroke to different brain areas (cortical and subcortical) induce specific deficits in bimanual and/or distal bim-MSkL, which behavioral components are involved in bim-MSkL, and whether damage to the motor, sensory and inter-hemispheric pathways specifically impairs proximal and/or distal bim-MSkL.
Official title: Exploring the Neural Substrates of Proximal and Distal Bimanual Motor Skill Learning Through Robotics and Multimodal Brain Imaging
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
160
Start Date
2023-04-17
Completion Date
2028-10
Last Updated
2024-12-16
Healthy Volunteers
Yes
Conditions
Interventions
REAplan®
motor skill learning with the REAplan® rehabilitation robot, to be performed with both arms
Dextrain Manipulandum®
motor skill learning with the Dextrain Manipulandum® dexterity tool to be performed with both hands
Locations (2)
CHU UCL Namur
Yvoir, Namur, Belgium
University Hospital CHU Dinant Godinne UCL
Yvoir, Belgium