Clinical Research Directory

Inclusion Criteria: * Any patient consuming 10 to 40 cigarettes per day * Woman or man aged 18 to 75 inclusive * Substance use disorder according to the DSM5 classification * Benefit from social security or benefit from it through a third party in accordance with French law on research involving the human person * Having signed the informed consent form after having received written information. Exclusion Criteria: * Disabling cognitive disorders * Patient under 18 or over 75 years old. * Patient with a psychological disorder or a psychiatric pathology requiring specialized follow-up * Patient with addiction to another product. * Cardiological pathologies that could compromise the participation of patients, detected by an ECG (only for patients who will be randomized in the experimental group). * Advanced pulmonary, renal, and hepatic diseases, or any unstable and serious medical conditions that could compromise the patient's participation in the study, subject to the judgment of the doctor * Pregnant or breastfeeding woman * Simultaneous participation in another trial * Employee of the investigator or of the clinical trial site * Patients protected by law * Patients who do not speak the French language * People not covered by state health insurance * Patients who in the opinion of the investigator are unable to complete the questionnaires * Patient claustrophobic or anxious about using the cabin * Patient allergic to a molecule present in nicotine substitutes