Clinical Research Directory

Inclusion Criteria: For patients in mental health care only: * Outpatients * Diagnosed during intake, the primary diagnosis being chronic bipolar disorder (type I or 2) or a chronic or recurrent severe depression in the narrower sense of the word * Receiving psychopharmacological treatment * Have had a physical and lifestyle Routine Outcome Monitoring measurement showing that three or more metabolic parameters were outside the normal range For patients in general practice (GP) only: * Diagnosis of depressive symptoms or depressive disorder in the past year as registered in the general practice electronic health record and coded according to the International Classification of Primary Care (ICPC) as P03 and P76, respectively, * At least mild depressive symptom level according to the Beck Depression Inventory-II (BDI) (score ≥14) * Body mass index ≥ 25 kg/m2 or increased waist circumference (\>88cm (women) of \>102cm (men)). For both patient groups: \- 18 years or older and capable to participate in the intervention according to the treating physician Availability of one or two people close to the patient (friends or family, preferably sharing the same household), i.e. to act as the buddy of the patient. Exclusion Criteria: * For GP patients only: current treatment in mental health care (GGZ in Dutch) * For GP patients only: severe somatic / neurological disease at the discretion of the GP * Currently participating in another lifestyle intervention * Insufficient proficiency in Dutch * Unability to read and write