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DIagnostic Biomarkers and Symptoms in Patients With Alzheimer's Disease and Lewy bodY Dementia
Sponsor: Danish Dementia Research Centre
Summary
This a study to improve diagnosis of dementia with Lewy bodies with RT-QuIC in different biospecimens.
Official title: DIagnostic Biomarkers and Symptoms in Patients With Alzheimer's Disease and Lewy bodY Dementia - DISPLAY
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
55
Start Date
2023-02-01
Completion Date
2032-12
Last Updated
2023-10-10
Healthy Volunteers
Yes
Interventions
Real-time quaking-induced conversion (RT-QuIC)
RT-QuIC measures the ability of alpha-synuclein (aSyn) to misfold other aSyn proteins and is an amplification technique.
Cognitive test
Minimal Mental State examination (MMSE), Montreal Cognitive Assessment (MoCA)
Motor examination
Unified Parkinsons Rating Scale (UPDRS)
Locations (1)
Danish Dementia Research Centre
Copenhagen, Denmark