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ACTIVE NOT RECRUITING
NCT05768425

DIagnostic Biomarkers and Symptoms in Patients With Alzheimer's Disease and Lewy bodY Dementia

Sponsor: Danish Dementia Research Centre

View on ClinicalTrials.gov

Summary

This a study to improve diagnosis of dementia with Lewy bodies with RT-QuIC in different biospecimens.

Official title: DIagnostic Biomarkers and Symptoms in Patients With Alzheimer's Disease and Lewy bodY Dementia - DISPLAY

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

55

Start Date

2023-02-01

Completion Date

2032-12

Last Updated

2023-10-10

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

Real-time quaking-induced conversion (RT-QuIC)

RT-QuIC measures the ability of alpha-synuclein (aSyn) to misfold other aSyn proteins and is an amplification technique.

DIAGNOSTIC_TEST

Cognitive test

Minimal Mental State examination (MMSE), Montreal Cognitive Assessment (MoCA)

DIAGNOSTIC_TEST

Motor examination

Unified Parkinsons Rating Scale (UPDRS)

Locations (1)

Danish Dementia Research Centre

Copenhagen, Denmark