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Role of Liquid Biopsies in HPV-associated Cancer Treatment Monitoring
Sponsor: The Institute of Molecular and Translational Medicine, Czech Republic
Summary
This trial will evaluate the possible benefits and the performance of liquid biopsies in HPV-associated cancer treatment monitoring. This study aims to find a combination of an adequately sensitive and specific sampling method and biomarkers for early risk stratification of disease recurrence.
Official title: Liquid Biopsies - a Possible Tool for Treatment Monitoring and Early Recurrence Detection in HPV-associated Diseases
Key Details
Gender
All
Age Range
18 Years - 99 Years
Study Type
OBSERVATIONAL
Enrollment
480
Start Date
2022-06-01
Completion Date
2026-12-01
Last Updated
2026-02-12
Healthy Volunteers
No
Interventions
Arm A - Diagnostic test: HPV detection in liquid biopsies
Patients will be asked to perform self-collection of gargle lavage samples. Oropharyngeal swabs, breath condensate, and blood samples will be taken by trained clinicians.
Arm B - Diagnostic test: HPV detection in liquid biopsies
Patients will be asked to perform cervicovaginal self-sampling using Evalyn Brush. Blood samples will be taken by trained clinicians.
Locations (1)
University Hospital Olomouc
Olomouc, Czechia