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Exercise to Slow Cardiovascular Ageing Progression
Sponsor: National Heart Centre Singapore
Summary
In ageing, deleterious alterations in cardiovascular (CV) structure and function increase risks of ageing-related cardiovascular disease (CVD). Investigators found that these CV alterations were associated with circulating serum metabolites, suggesting a metabolic basis to CV ageing. Investigators hypothesize that modification of these metabolites by intervention, such as exercise, may retard CV alterations and reduce CVD in ageing.
Key Details
Gender
All
Age Range
21 Years - 100 Years
Study Type
OBSERVATIONAL
Enrollment
450
Start Date
2023-05-01
Completion Date
2050-12-31
Last Updated
2025-06-05
Healthy Volunteers
Yes
Conditions
Locations (1)
National Heart Centre Singapore
Singapore, Singapore, Singapore