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SMC Radiation Oncology Breast Cancer Cohort Study
Sponsor: Samsung Medical Center
Summary
The goal of this observational study is to learn about toxicities and cosmetic outcomes in breast cancer patients treated with hypofractionated radiotherapy. The main question it aims to answer are: * Changes in breast skin * Factors related to breast skin changes * Patient-reported outcomes * Cosmetic outcomes Participants will be assessed by multi-dimensional methods before and after radiotherapy: * Photographs * Fibrometer * Questionnaires (BREAST-Q) * CTCAE version 4.03 evaluated by treating physicians
Official title: Registry for Analysis of Impact of Radiation Dose to Skin on Cosmetic Outcome and Patient-reported Outcomes in Patients With Breast Cancer Treated With Radiation Therapy
Key Details
Gender
FEMALE
Age Range
18 Years - 85 Years
Study Type
OBSERVATIONAL
Enrollment
500
Start Date
2021-01-01
Completion Date
2030-12-31
Last Updated
2025-06-29
Healthy Volunteers
No
Conditions
Interventions
Hypofractionated radiation therapy
Both 3-week and 1-week hypofractioanted radiation therapy are allowed. (simultaneous or sequential tumor bed boost is allowed.) A 3-week regimen includes 42.4 Gy in 16 fractions. A 1-week regimen includes 26 Gy in 5 fractions or 28.5 Gy in 3 fractions, 30 Gy in 5 fractions.
Locations (1)
Samsung Medical Center
Seoul, South Korea