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Syncope Trial to Understand Tilt Testing or ECG Recording Tenth Prevention of Syncope Trial
Sponsor: University of Calgary
Summary
The Study To Understand Tilt Tests versus Extended Recordings (STUTTER, POST 10) will test the hypothesis that first performing a diagnostic HUT in older patients with syncope of unknown cause will provide earlier and more diagnoses than inserting an ICM.
Official title: Syncope Trial to Understand Tilt Testing or ECG Recording. Tenth Prevention of Syncope
Key Details
Gender
All
Age Range
50 Years - 110 Years
Study Type
INTERVENTIONAL
Enrollment
144
Start Date
2023-05-01
Completion Date
2026-12-31
Last Updated
2024-12-19
Healthy Volunteers
No
Conditions
Interventions
Diagnostic Test: Head Up Tilt Table (HUT)
Participant randomized to open-label diagnostic strategy. Results and all follow-up care to be in the hands of treating cardiologist as this is a pragmatic study. the early HUT \[protocol: supine pre-tilt phase 5 min, un-medicated HUT to 70 degrees for 20 minutes; if response negative then 400 μg of sublingual nitroglycerin and continued 70 degree tilt for 20 minutes\]
Device: Implantable Loop Recorder
ILR is a small subcutaneously implanted device, lasting up to 3 years, that records heart rhythms, and which may be either auto-triggered or patientactivated.
Locations (1)
University of Calgary
Calgary, Alberta, Canada