Clinical Research Directory
Browse clinical research sites, groups, and studies.
Use of Blood Biomarkers for the Early Diagnosis of Hepatocellular Carcinoma (HCC)
Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Summary
The objective of this observational study is to evaluate the clinical utility of the combined assay of 3 biomarkers: α-FP, α-FP-L3 and DCP (simultaneously measured by µTASWakoTM i30 automated in vitro diagnostic system) in high-risk subjects to develop this neoplasm. In particular, it aims to: * Evaluate the clinical utility of the combined use of α-FP, α-FP-L3 and DCP in predicting the onset of HEPATOCARCINOMA (HCC); * Evaluate the performance of GALAD and GALADUS scores in the early diagnosis of HCC; * Evaluate the association between the levels of the three biomarkers (individually and in combination with each other) and the stage of HCC
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
60
Start Date
2023-02-24
Completion Date
2025-01-27
Last Updated
2024-04-08
Healthy Volunteers
No
Conditions
Interventions
Biomarker dosage
The simultaneous dosage of the 3 serum biomarkers will be performed at the Clinical Pathology Laboratory, using the instrument: µTASWakoTM i30 (Micro Total Analysis System) - Fujifilm.
Locations (1)
RCCS "Saverio de Bellis"
Castellana Grotte, Bari, Italy