Clinical Research Directory

Inclusion Criteria: * Adult * Hemorrhoidal disease grade II and III * American Society of Anesthesiologists (ASA) classification I-III. Exclusion Criteria: * Previous surgical treatment for hemorrhoids by all methods except rubber band ligation or sclerosing injection therapy within the last 3 years. * Previous surgical treatment with rubber band ligation or injection therapy within the last 2 months. * More than three surgical treatments with rubber band ligation or sclerosing injection therapy within the last 3 years. * Under medication with immunosuppressive drugs and/or anticoagulant drugs (not including 75mg acetylsalicylic acid) and not able to interrupt the anticoagulant drug medication or replace it with low molecular weight heparin for 5 days. * Have ulcerative colitis, Crohn's disease or other intestinal inflammatory disease or presence of inflamed or thickened mucosa of the rectum. * Presence of anal fissure, anal stenosis, stricture, fistulas or ulcers in the rectal area. * The rectum has not been prepared prior to the investigation with rectal enema and is contaminated with feces that cannot easily be removed. * Have schizophrenia, untreated depression or other mental illness or conditions that may affect judgment, sensation of pain or inability to complete the follow-up. * Under medication of morphine or other strong painkillers, not including paracetamol. * Fecal incontinence (not including soiling due to hemorrhoidal disease), or conditions with impaired sensation in the rectal area or impaired function of the anal sphincter. * Previous rectal radiation. * Rectal cancer or previous surgery due to rectal cancer. * Pregnancy * Hypercoagulability disorders or diseases that result in increased risk of bleeding. * Impaired immune system or condition that increases the risk of infection.